Make sure you have a folder named Bios in the PCSX2 1.0.0 folder, if not create one in there. Put the bios files in there. Then run the program, click the config and choose the Plugin/Bios selector. In the next window select the BIOS tab at the top middle (between Plugins, Folders). Select the bios for the game region USA for NTSC or Europe for PAL. Apply settings. press ok.
Use Linuz Iso CDVD plugin. Choose this in the CDVD Plugins.
Go back to main menu, circle in the "Iso" option in CDVD tab then choose the "Iso Selector" and browse to your where you put your Iso and select it. When done select System tab and Boot CDVD.